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Nbp2 targets the Ptc1-type 2C Ser/Thr phosphatase to the HOG MAPK pathway
The yeast high osmolarity glycerol (HOG) pathway signals via the Pbs2 MEK and the Hog1 MAPK, whose activity requires phosphorylation of Thr and Tyr in the activation loop. The Ptc1-type 2C Ser/Thr phosphatase (PP2C) inactivates Hog1 by dephosphorylating phospho-Thr, while the Ptp2 and Ptp3 protein t...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2004
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1271746/ https://ncbi.nlm.nih.gov/pubmed/14685261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600036 |
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