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A Chemically Modified Tetracycline (CMT-3) Is a New Antifungal Agent

Several chemically modified tetracycline analogs (CMTs), which were chemically modified to eliminate their antibacterial efficacy, were unexpectedly found to have antifungal properties. Of 10 CMTs screened in vitro, all exhibited antifungal activities, although their efficacies varied. Among these c...

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Bibliographic Details
Main Authors: Liu, Yu, Ryan, Maria E., Lee, Hsi-Ming, Simon, Sanford, Tortora, George, Lauzon, Carol, Leung, Michael K., Golub, Lorne M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC127171/
https://ncbi.nlm.nih.gov/pubmed/11959581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.5.1447-1454.2002
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