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A Chemically Modified Tetracycline (CMT-3) Is a New Antifungal Agent

Several chemically modified tetracycline analogs (CMTs), which were chemically modified to eliminate their antibacterial efficacy, were unexpectedly found to have antifungal properties. Of 10 CMTs screened in vitro, all exhibited antifungal activities, although their efficacies varied. Among these c...

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Autors principals: Liu, Yu, Ryan, Maria E., Lee, Hsi-Ming, Simon, Sanford, Tortora, George, Lauzon, Carol, Leung, Michael K., Golub, Lorne M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC127171/
https://ncbi.nlm.nih.gov/pubmed/11959581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.5.1447-1454.2002
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