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Interaction between Grapefruit Juice and Praziquantel in Humans

After a single oral dose of praziquantel with 250 ml of grapefruit juice, the area under the concentration-time curve and the maximum concentration in plasma of praziquantel (C(max)) were significantly increased (C(max) for water treatment, 637.71 ± 128.5 ng/ml; and C(max) for grapefruit juice treat...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Castro, Nelly, Jung, Helgi, Medina, Roberto, González-Esquivel, Dinora, Lopez, Mario, Sotelo, Julio
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2002
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127135/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11959616/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.5.1614-1616.2002
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