Hemofiltrate CC Chemokine 1[9-74] Causes Effective Internalization of CCR5 and Is a Potent Inhibitor of R5-Tropic Human Immunodeficiency Virus Type 1 Strains in Primary T Cells and Macrophages

Proteolytic processing of the abundant plasmatic human CC chemokine 1 (HCC-1) generates a truncated form, HCC-1[9-74], which is a potent agonist of CCR1, CCR3, and CCR5; promotes calcium influx and chemotaxis of T lymphoblasts, monocytes, and eosinophils; and inhibits infection by CCR5-tropic human...

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Hlavní autoři: Münch, Jan, Ständker, Ludger, Pöhlmann, Stefan, Baribaud, Frédéric, Papkalla, Armin, Rosorius, Olaf, Stauber, Roland, Sass, Gabriele, Heveker, Nikolaus, Adermann, Knut, Escher, Sylvia, Klüver, Enno, Doms, Robert W., Forssmann, Wolf-Georg, Kirchhoff, Frank
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
Témata:
Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC127102/
https://ncbi.nlm.nih.gov/pubmed/11897579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.4.982-990.2002
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