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Cleavage of dsRNAs hyper-edited by ADARs occurs at preferred editing sites

Long double-stranded RNAs (dsRNAs) may undergo covalent modification (hyper-editing) by adenosine deaminases that act on RNA (ADARs), whereby up to 50–60% of adenosine residues are converted to inosine. Previously, we have described a ribonuclease activity in various cell extracts that specifically...

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Hlavní autoři: Scadden, A. D. J., O'Connell, M. A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1270950/
https://ncbi.nlm.nih.gov/pubmed/16254076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki909
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