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Effect of the insulin iodination on the reactivity of the inter-chain disulphide bonds towards sodium sulphite

Insulin iodination interferes with the ability of the interchain S·S bonds to react with sulphite at pH7. In insulin samples containing more than 5 iodine atoms/monomer unit, only one S·S bond/molecule reacts. The effect must be related to the substitution of the iodine into the tyrosyl groups, whic...

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Bibliografiske detaljer
Main Authors: Rosa, U., Massaglia, A., Pennisi, F., Cozzani, I., Rossi, C. A.
Format: Artigo
Sprog:Inglês
Udgivet: 1967
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1270422/
https://ncbi.nlm.nih.gov/pubmed/6067894
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