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Multiple Interactions of Cimetidine and Probenecid with Valaciclovir and Its Metabolite Acyclovir

The effects of probenecid and cimetidine on the pharmacokinetics of valaciclovir and its metabolite acyclovir have been investigated. Twelve healthy male volunteers participated in this open single-dose study with a four-way-crossover randomized and balanced design. At the first of four administrati...

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Autori principali: De Bony, F., Tod, M., Bidault, R., On, N. T., Posner, J., Rolan, P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC127018/
https://ncbi.nlm.nih.gov/pubmed/11796358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.2.458-463.2002
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