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Pharmacodynamics of Trovafloxacin and Levofloxacin against Bacteroides fragilis in an In Vitro Pharmacodynamic Model

An in vitro pharmacodynamic investigation was conducted to explore whether the area under the concentration time curve from 0 to 24 h (AUC(0–24))/MIC ratio could predict fluoroquinolone performance against Bacteroides fragilis. An in vitro model was used to generate kill curves for trovafloxacin (TV...

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Published in:Antimicrob Agents Chemother
Main Authors: Peterson, M. L., Hovde, L. B., Wright, D. H., Brown, G. H., Hoang, A. D., Rotschafer, J. C.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2002
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126996/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11751135/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.1.203-210.2002
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