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Pharmacodynamics of Gatifloxacin against Streptococcus pneumoniae in an In Vitro Pharmacokinetic Model: Impact of Area under the Curve/MIC Ratios on Eradication
Previous studies have demonstrated that fluoroquinolone area under the curve (AUC)/MIC ratios of 30 to 50 are sufficient to eradicate pneumococci from in vitro pharmacokinetic models (IVPMs). However, more systematic studies of the impact of AUC/MIC ratios on the antipneumococcal activities of fluor...
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格式: | Artigo |
語言: | Inglês |
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American Society for Microbiology
2002
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC126977/ https://ncbi.nlm.nih.gov/pubmed/11751113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.1.69-74.2002 |
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