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Pharmacokinetics and Inflammatory Fluid Penetration of Intravenous Daptomycin in Volunteers

The lipopeptide antimicrobial daptomycin was administered intravenously at a dose of 4 mg/kg of body weight to seven healthy male volunteers. The concentrations of daptomycin in plasma, cantharidin-induced inflammatory fluid, and urine were measured by a microbiological assay. The mean ± standard de...

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Detalhes bibliográficos
Main Authors: Wise, R., Gee, T., Andrews, J. M., Dvorchik, B., Marshall, G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC126970/
https://ncbi.nlm.nih.gov/pubmed/11751107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.1.31-33.2002
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