Bradykinin-12-lipoxygenase-VR1 signaling pathway for inflammatory hyperalgesia

The capsaicin-sensitive vanilloid receptor (VR1) was recently shown to play an important role in inflammatory pain (hyperalgesia), but the underlying mechanism is unknown. We hypothesized that pain-producing inflammatory mediators activate capsaicin receptors by inducing the production of fatty acid...

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Autori principali: Shin, Jieun, Cho, Hawon, Hwang, Sun Wook, Jung, Jooyoung, Shin, Chan Young, Lee, Soon-Youl, Kim, So Hee, Lee, Myung Gull, Choi, Young Hae, Kim, Jinwoong, Haber, Nicole Alessandri, Reichling, David B., Khasar, Sachia, Levine, Jon D., Oh, Uhtaek
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2002
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC126639/
https://ncbi.nlm.nih.gov/pubmed/12097645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.152002699
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