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Inhibition of Actomyosin ATPase Activity by Troponin-Tropomyosin without Blocking the Binding of Myosin to Actin

Relaxation of vertebrate skeletal muscle is thought to occur in the absence of Ca(2+) as a result of tropomyosin physically blocking the binding of myosin to actin. This steric blocking model of muscle relaxation predicts that myosin subfragment 1 (S-1) will not bind to actin under conditions where...

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Detalhes bibliográficos
Main Authors: Chalovich, Joseph M., Eisenberg, Evan
Formato: Artigo
Idioma:Inglês
Publicado em: 1982
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1266292/
https://ncbi.nlm.nih.gov/pubmed/6460759
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