Single-stranded DNA mimicry in the p53 transactivation domain interaction with replication protein A

One of many protein–protein interactions modulated upon DNA damage is that of the single-stranded DNA-binding protein, replication protein A (RPA), with the p53 tumor suppressor. Here we report the crystal structure of RPA residues 1–120 (RPA70N) bound to the N-terminal transactivation domain of p53...

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Detalhes bibliográficos
Main Authors: Bochkareva, Elena, Kaustov, Lilia, Ayed, Ayeda, Yi, Gwan-Su, Lu, Ying, Pineda-Lucena, Antonio, Liao, Jack C. C., Okorokov, Andrei L., Milner, Jo, Arrowsmith, Cheryl H., Bochkarev, Alexey
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1266094/
https://ncbi.nlm.nih.gov/pubmed/16234232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504614102
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