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Selection of optimal oligonucleotide probes for microarrays using multiple criteria, global alignment and parameter estimation
The oligonucleotide specificity for microarray hybridization can be predicted by its sequence identity to non-targets, continuous stretch to non-targets, and/or binding free energy to non-targets. Most currently available programs only use one or two of these criteria, which may choose ‘false’ speci...
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Main Authors: | , , |
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格式: | Artigo |
語言: | Inglês |
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Oxford University Press
2005
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在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1266071/ https://ncbi.nlm.nih.gov/pubmed/16246912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki914 |
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