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Selection of optimal oligonucleotide probes for microarrays using multiple criteria, global alignment and parameter estimation

The oligonucleotide specificity for microarray hybridization can be predicted by its sequence identity to non-targets, continuous stretch to non-targets, and/or binding free energy to non-targets. Most currently available programs only use one or two of these criteria, which may choose ‘false’ speci...

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Detalhes bibliográficos
Main Authors: Li, Xingyuan, He, Zhili, Zhou, Jizhong
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1266071/
https://ncbi.nlm.nih.gov/pubmed/16246912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki914
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