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Acidification of rat TRPV1 alters the kinetics of capsaicin responses

TRPV1 (vanilloid receptor 1) receptors are activated by a variety of ligands such as capsaicin, as well as by acidic conditions and temperatures above 42°C. These activators can enhance the potency of one another, shifting the activation curve for TRPV1 to the left. In this study, for example, we ob...

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Detalhes bibliográficos
Main Authors: Neelands, Torben R, Jarvis, Michael F, Han, Ping, Faltynek, Connie R, Surowy, Carol S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1266034/
https://ncbi.nlm.nih.gov/pubmed/16191202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-1-28
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