Chaperone-Mediated Folding and Maturation of the Penicillin Acylase Precursor in the Cytoplasm of Escherichia coli

Expression of the leaderless pac gene (LL pac), which lacks the coding region for the signal peptide of penicillin acylase (PAC), in Escherichia coli was conducted. It was demonstrated that the PAC precursor, proPAC, can be produced and even processed to form mature PAC in the cytoplasm, indicating...

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Detalhes bibliográficos
Main Authors: Xu, Yali, Weng, Chiao-Ling, Narayanan, Niju, Hsieh, Ming-Yi, Anderson, William A., Scharer, Jeno M., Moo-Young, Murray, Chou, C. Perry
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Genetics and Molecular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1265976/
https://ncbi.nlm.nih.gov/pubmed/16204545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.71.10.6247-6253.2005
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