Chaperone-Mediated Folding and Maturation of the Penicillin Acylase Precursor in the Cytoplasm of Escherichia coli

Expression of the leaderless pac gene (LL pac), which lacks the coding region for the signal peptide of penicillin acylase (PAC), in Escherichia coli was conducted. It was demonstrated that the PAC precursor, proPAC, can be produced and even processed to form mature PAC in the cytoplasm, indicating...

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Autors principals: Xu, Yali, Weng, Chiao-Ling, Narayanan, Niju, Hsieh, Ming-Yi, Anderson, William A., Scharer, Jeno M., Moo-Young, Murray, Chou, C. Perry
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
Matèries:
Genetics and Molecular Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1265976/
https://ncbi.nlm.nih.gov/pubmed/16204545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.71.10.6247-6253.2005
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