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All neuropathies great and small

Autosomal-dominant pure hereditary spastic paraplegia (AD-HSP) is characterized by the degeneration of long axons in corticospinal tracts and dorsal columns, resulting in spasticity and difficulty walking. Mutations in the SPG4 gene product spastin are the predominant genetic lesions associated with...

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Main Authors: Penny, Ellen B., McCabe, Brian D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Clinical Investigation 2005
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1265885/
https://ncbi.nlm.nih.gov/pubmed/16276409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27003
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