GM-CSF action in the CNS decreases food intake and body weight

Many proinflammatory cytokines, such as leptin, play key roles in dynamic regulation of energy expenditure and food intake. The present work tested a role for the proinflammatory cytokine GM-CSF. Central but not peripheral administration of GM-CSF to adult rats significantly decreased food intake an...

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Bibliographische Detailangaben
Hauptverfasser: Reed, Jacquelyn A., Clegg, Deborah J., Blake Smith, Kathleen, Tolod-Richer, Emeline G., Matter, Emily K., Picard, Lara S., Seeley, Randy J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2005
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1265876/
https://ncbi.nlm.nih.gov/pubmed/16276414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI25681
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