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A-Kinase-Anchoring Protein 95 Functions as a Potential Carrier for the Nuclear Translocation of Active Caspase 3 through an Enzyme-Substrate-Like Association

Caspase-mediated proteolysis is a critical and central element of the apoptotic process, and caspase 3, one of the effector caspases, is proposed to play essential roles in the nuclear morphological changes of apoptotic cells. Although many substrates for caspase 3 localize in the nucleus and caspas...

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Autores principales: Kamada, Shinji, Kikkawa, Ushio, Tsujimoto, Yoshihide, Hunter, Tony
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1265837/
https://ncbi.nlm.nih.gov/pubmed/16227597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.21.9469-9477.2005
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