Structure-Function Analysis of the Human TFIIB-Related Factor II Protein Reveals an Essential Role for the C-Terminal Domain in RNA Polymerase III Transcription

The transcription factors TFIIB, Brf1, and Brf2 share related N-terminal zinc ribbon and core domains. TFIIB bridges RNA polymerase II (Pol II) with the promoter-bound preinitiation complex, whereas Brf1 and Brf2 are involved, as part of activities also containing TBP and Bdp1 and referred to here a...

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Bibliographic Details
Main Authors: Saxena, Ashish, Ma, Beicong, Schramm, Laura, Hernandez, Nouria
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1265830/
https://ncbi.nlm.nih.gov/pubmed/16227591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.21.9406-9418.2005
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