Global Gene Expression Profiling Reveals Widespread yet Distinctive Translational Responses to Different Eukaryotic Translation Initiation Factor 2B-Targeting Stress Pathways

Global inhibition of protein synthesis is a hallmark of many cellular stress conditions. Even though specific mRNAs defy this (e.g., yeast GCN4 and mammalian ATF4), the extent and variation of such resistance remain uncertain. In this study, we have identified yeast mRNAs that are translationally ma...

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Bibliografiske detaljer
Main Authors: Smirnova, Julia B., Selley, Julian N., Sanchez-Cabo, Fatima, Carroll, Kathleen, Eddy, A. Alan, McCarthy, John E. G., Hubbard, Simon J., Pavitt, Graham D., Grant, Chris M., Ashe, Mark P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Gene Expression
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1265828/
https://ncbi.nlm.nih.gov/pubmed/16227585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.21.9340-9349.2005
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