Long-Chain Base Kinase Lcb4 Is Anchored to the Membrane through Its Palmitoylation by Akr1

Sphingoid long-chain base kinase Lcb4 catalyzes the production of the bioactive lipid molecules the long-chain base 1-phosphates. Although Lcb4 has no apparent transmembrane-spanning domain, it is tightly associated with the membrane. Here, we demonstrate that Lcb4 is modified by palmitoylation. Thi...

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Библиографические подробности
Главные авторы: Kihara, Akio, Kurotsu, Fumiko, Sano, Takamitsu, Iwaki, Soichiro, Igarashi, Yasuyuki
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2005
Предметы:
Intracellular Trafficking
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1265802/
https://ncbi.nlm.nih.gov/pubmed/16227572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.21.9189-9197.2005
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