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Translational Deregulation in PDK-1(−/−) Embryonic Stem Cells
PDK-1 is a protein kinase that is critical for the activation of many downstream protein kinases in the AGC superfamily, through phosphorylation of the activation loop site on these substrates. Cells lacking PDK-1 show decreased activity of these protein kinases, including protein kinase B (PKB) and...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1265760/ https://ncbi.nlm.nih.gov/pubmed/16166629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.19.8465-8475.2005 |
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