Translational Deregulation in PDK-1(−/−) Embryonic Stem Cells

PDK-1 is a protein kinase that is critical for the activation of many downstream protein kinases in the AGC superfamily, through phosphorylation of the activation loop site on these substrates. Cells lacking PDK-1 show decreased activity of these protein kinases, including protein kinase B (PKB) and...

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Bibliografiske detaljer
Main Authors: Tominaga, Yuichi, Tamgüney, Tanja, Kolesnichenko, Marina, Bilanges, Benoit, Stokoe, David
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2005
Fag:
Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1265760/
https://ncbi.nlm.nih.gov/pubmed/16166629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.19.8465-8475.2005
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