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Induction of COX-2 by LPS in macrophages is regulated by Tpl2-dependent CREB activation signals
Macrophage activation by bacterial lipopolysaccharide (LPS) promotes the secretion of pro-inflammatory cytokines, such as tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β), and of secondary mediators, such as leukotrienes and prostaglandins (PGs). Mice lacking the gene encoding the serine/t...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC126277/ https://ncbi.nlm.nih.gov/pubmed/12234923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf478 |
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