Low pH immobilizes and kills human leukocytes and prevents transmission of cell-associated HIV in a mouse model

BACKGROUND: Both cell-associated and cell-free HIV virions are present in semen and cervical secretions of HIV-infected individuals. Thus, topical microbicides may need to inactivate both cell-associated and cell-free HIV to prevent sexual transmission of HIV/AIDS. To determine if the mild acidity o...

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Detalhes bibliográficos
Main Authors: Olmsted, Stuart S, Khanna, Kristen V, Ng, Erina M, Whitten, Steven T, Johnson, Owen N, Markham, Richard B, Cone, Richard A, Moench, Thomas R
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1262719/
https://ncbi.nlm.nih.gov/pubmed/16194280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-5-79
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