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Epigenetic predisposition to expression of TIMP1 from the human inactive X chromosome

BACKGROUND: X inactivation in mammals results in the transcriptional silencing of an X chromosome in females, and this inactive X acquires many of the epigenetic features of silent chromatin. However, not all genes on the inactive X are silenced, and we have examined the TIMP1 gene, which has variab...

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Detalhes bibliográficos
Main Authors: Anderson, Catherine L, Brown, Carolyn J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1262707/
https://ncbi.nlm.nih.gov/pubmed/16194278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-6-48
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