Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen Induces a Strong Bend on Binding to Terminal Repeat DNA

During latency, the Kaposi's sarcoma-associated herpesvirus genome is maintained as a circular episome, replicating in synchrony with host chromosomes. Replication requires the latency-associated nuclear antigen (LANA) and an origin of latent DNA replication located in the viral terminal repeat...

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Detalhes bibliográficos
Main Authors: Wong, Lai-Yee, Wilson, Angus C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1262613/
https://ncbi.nlm.nih.gov/pubmed/16227305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.21.13829-13836.2005
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