Prophylactic Alpha Interferon Treatment Increases the Therapeutic Index of Oncolytic Vesicular Stomatitis Virus Virotherapy for Advanced Hepatocellular Carcinoma in Immune-Competent Rats

Vesicular stomatitis virus (VSV) is a negative-strand RNA virus with intrinsic oncolytic specificity due to substantially attenuated antiviral responses in many tumors. We have recently reported that recombinant VSV vector can be used as an effective oncolytic agent to safely treat multifocal hepato...

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Main Authors: Shinozaki, Katsunori, Ebert, Oliver, Suriawinata, Arief, Thung, Swan N., Woo, Savio L. C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
Assuntos:
Gene Delivery
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1262571/
https://ncbi.nlm.nih.gov/pubmed/16227290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.21.13705-13713.2005
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