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Regulation of adenine nucleotide concentration at endothelium-fluid interface by viscous shear flow.

The action of adenine nucleotides on vascular endothelial cells is apparently mediated by the local flow conditions. Because nucleotides are sequentially degraded from ATP-->ADP-->AMP-->adenosine by ecto-enzymes at the endothelial surface, it has been hypothesized that the observed flow eff...

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Bibliographic Details
Main Authors: Shen, J, Gimbrone, M A, Luscinskas, F W, Dewey, C F
Format: Artigo
Language:Inglês
Published: 1993
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1262450/
https://ncbi.nlm.nih.gov/pubmed/8494987
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