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Dissociation of the dimeric SecA ATPase during protein translocation across the bacterial membrane

The ATPase SecA mediates post-translational translocation of precursor proteins through the SecYEG channel of the bacterial inner membrane. We show that SecA, up to now considered to be a stable dimer, is actually in equilibrium with a small fraction of monomers. In the presence of membranes contain...

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Autori principali: Or, Eran, Navon, Amiel, Rapoport, Tom
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC126201/
https://ncbi.nlm.nih.gov/pubmed/12198149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf471
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