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Leishmania LPG3 encodes a GRP94 homolog required for phosphoglycan synthesis implicated in parasite virulence but not viability

Leishmania promastigotes express an abundant cell surface glycoconjugate, lipophosphoglycan (LPG). LPG contains a polymer of the disaccharide-phosphate repeat unit Galβ1,4Manα1-PO(4), shared by other developmentally regulated molecules implicated in parasite virulence. Functional complementation of...

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Detalhes bibliográficos
Main Authors: Descoteaux, Albert, Avila, Herbert A., Zhang, Kai, Turco, Salvatore J., Beverley, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC126187/
https://ncbi.nlm.nih.gov/pubmed/12198148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf447
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