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Ca(2+)-dependent block of CREB–CBP transcription by repressor DREAM
The calcium-binding protein DREAM binds specifically to DRE sites in the DNA and represses transcription of target genes. Derepression at DRE sites following PKA activation depends on a specific interaction between αCREM and DREAM. Two leucine-charged residue-rich domains (LCD) located in the kinase...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2002
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC126180/ https://ncbi.nlm.nih.gov/pubmed/12198160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf440 |
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