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E1A expression dysregulates IL-8 production and suppresses IL-6 production by lung epithelial cells

BACKGROUND: The adenoviral protein E1A has been proposed to play a role in the pathophysiology of COPD, in particular by increasing IL-8 gene transcription of lung epithelial cells in response to cigarette smoke-constituents such as LPS. As IL-8 production is also under tight post-transcriptional co...

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Autors principals: van den Berg, Arjen, Snoek, Mieke, Jansen, Henk M, Lutter, René
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1261537/
https://ncbi.nlm.nih.gov/pubmed/16185356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-6-111
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