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The presence of two UvrB subunits in the UvrAB complex ensures damage detection in both DNA strands

It is generally accepted that the damage recognition complex of nucleotide excision repair in Escherichia coli consists of two UvrA and one UvrB molecule, and that in the preincision complex UvrB binds to the damage as a monomer. Using scanning force microscopy, we show here that the damage recognit...

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Udgivet i:EMBO J
Principais autores: Verhoeven, Esther E.A., Wyman, Claire, Moolenaar, Geri F., Goosen, Nora
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2002
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126143/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12145219/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf396
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