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Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-κB

AP-1 family transcription factors have been implicated in the control of proliferation, apoptosis and malignant transformation. However, their role in oncogenesis is unclear and no recurrent alterations of AP-1 activities have been described in human cancers. Here, we show that constitutively activa...

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Détails bibliographiques
Auteurs principaux: Mathas, Stephan, Hinz, Michael, Anagnostopoulos, Ioannis, Krappmann, Daniel, Lietz, Andreas, Jundt, Franziska, Bommert, Kurt, Mechta-Grigoriou, Fatima, Stein, Harald, Dörken, Bernd, Scheidereit, Claus
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC126136/
https://ncbi.nlm.nih.gov/pubmed/12145210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf389
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