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M-LDH serves as a sarcolemmal K(ATP) channel subunit essential for cell protection against ischemia
ATP-sensitive K(+) (K(ATP)) channels in the heart are normally closed by high intracellular ATP, but are activated during ischemia to promote cellular survival. These channels are heteromultimers composed of Kir6.2 subunit, an inwardly rectifying K(+) channel core, and SUR2A, a regulatory subunit im...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC126135/ https://ncbi.nlm.nih.gov/pubmed/12145195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf388 |
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