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Structural Evolution of the Protein Kinase–Like Superfamily

The protein kinase family is large and important, but it is only one family in a larger superfamily of homologous kinases that phosphorylate a variety of substrates and play important roles in all three superkingdoms of life. We used a carefully constructed structural alignment of selected kinases a...

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Detalhes bibliográficos
Main Authors: Scheeff, Eric D, Bourne, Philip E
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1261164/
https://ncbi.nlm.nih.gov/pubmed/16244704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0010049
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