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The splicing of U12-type introns can be a rate-limiting step in gene expression

Some protein-coding genes in metazoan genomes contain a minor class of introns that are excised by a distinct, low-abundance spliceosome. We have developed a quantitative RT–PCR assay that allows comparison of the relative rates of intron removal from the transcripts present in a pre-mRNA population...

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Detalhes bibliográficos
Main Authors: Patel, Abhijit A., McCarthy, Matthew, Steitz, Joan A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC126102/
https://ncbi.nlm.nih.gov/pubmed/12110592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf297
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