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Structural basis for the interaction between NTF2 and nucleoporin FxFG repeats

Interactions with nucleoporins containing FxFG-repeat cores are crucial for the nuclear import of RanGDP mediated by nuclear transport factor 2 (NTF2). We describe here the 1.9 Å resolution crystal structure of yeast NTF2-N77Y bound to a FxFG-nucleoporin core, which provides a basis for understandin...

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Detalhes bibliográficos
Main Authors: Bayliss, Richard, Leung, Sara W., Baker, Rosanna P., Quimby, B.Booth, Corbett, Anita H., Stewart, Murray
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC126060/
https://ncbi.nlm.nih.gov/pubmed/12065398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf305
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