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Structural basis for the interaction between NTF2 and nucleoporin FxFG repeats

Interactions with nucleoporins containing FxFG-repeat cores are crucial for the nuclear import of RanGDP mediated by nuclear transport factor 2 (NTF2). We describe here the 1.9 Å resolution crystal structure of yeast NTF2-N77Y bound to a FxFG-nucleoporin core, which provides a basis for understandin...

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Udgivet i:EMBO J
Principais autores: Bayliss, Richard, Leung, Sara W., Baker, Rosanna P., Quimby, B.Booth, Corbett, Anita H., Stewart, Murray
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2002
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126060/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12065398/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf305
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