Synapsis of DNA ends by DNA-dependent protein kinase

The catalytic subunit of DNA-dependent protein kinase (DNA-PK(CS)) is required for a non-homologous end-joining pathway that repairs DNA double-strand breaks produced by ionizing radiation or V(D)J recombination; however, its role in this pathway has remained obscure. Using a neutravidin pull-down a...

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Bibliografiske detaljer

Udgivet i:	EMBO J
Principais autores:	DeFazio, Lisa G., Stansel, Rachel M., Griffith, Jack D., Chu, Gilbert
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 2002
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126055/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12065431/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf299
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