Probing conformational changes in the nicotinic acetylcholine receptor by Fourier transform infrared difference spectroscopy.

We have developed a Fourier transform infrared (FTIR) difference method for probing conformational changes that occur upon the binding of ligands to the nicotinic acetylcholine receptor (nAChR). Our approach is to deposit reconstituted nAChR membranes in a thin film on the surface of a germanium int...

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Bibliografische gegevens
Hoofdauteurs: Baenziger, J E, Miller, K W, McCarthy, M P, Rothschild, K J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1992
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1260486/
https://ncbi.nlm.nih.gov/pubmed/1600101
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