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Characterization of an anti-apoptotic glycoprotein encoded by Kaposi’s sarcoma-associated herpesvirus which resembles a spliced variant of human survivin

We have investigated the expression and function of a novel protein encoded by open reading frame (ORF) K7 of Kaposi’s sarcoma-associated herpesvirus (KSHV). Computational analyses revealed that K7 is structurally related to survivin-ΔEx3, a splice variant of human survivin that protects cells from...

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Udgivet i:EMBO J
Principais autores: Wang, Hsei-Wei, Sharp, Tyson V., Koumi, Andrew, Koentges, Georgy, Boshoff, Chris
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2002
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126038/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12032073/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/21.11.2602
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