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Specific interaction of IP(6) with human Ku70/80, the DNA-binding subunit of DNA-PK

In eukaryotic cells, DNA double-strand breaks can be repaired by non-homologous end-joining, a process dependent upon Ku70/80, XRCC4 and DNA ligase IV. In mammals, this process also requires DNA-PK(cs), the catalytic subunit of the DNA-dependent protein kinase DNA-PK. Previously, inositol hexakispho...

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Detalles Bibliográficos
Publicado en:EMBO J
Principais autores: Hanakahi, Les A., West, Stephen C.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2002
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125973/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11953323/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/21.8.2038
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