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GAGA can mediate enhancer function in trans by linking two separate DNA molecules

Enhancers have been defined as cis-acting DNA sequences that stimulate transcription from a linked promoter in a distance- and orientation-independent manner. How enhancers activate gene transcription over vast chromosomal distances within metazoan genomes remains poorly understood. Here, we show th...

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Udgivet i:EMBO J
Principais autores: Mahmoudi, Tokameh, Katsani, Katerina R., Verrijzer, C.Peter
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2002
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125945/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11927561/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/21.7.1775
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