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Crystal structures of two intermediates in the assembly of the papillomavirus replication initiation complex

Initiation of DNA replication of the papillomavirus genome is a multi-step process involving the sequential loading of viral E1 protein subunits onto the origin of replication. Here we have captured structural snapshots of two sequential steps in the assembly process. Initially, an E1 dimer binds to...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Enemark, Eric J., Stenlund, Arne, Joshua-Tor, Leemor
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC125917/
https://ncbi.nlm.nih.gov/pubmed/11889054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.6.1487
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