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Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae

The major pathways of mRNA turnover in eukaryotic cells are initiated by shortening of the poly(A) tail. Recent work has identified Ccr4p and Pop2p as components of the major cytoplasmic deadenylase in yeast. We now demonstrate that CCR4 encodes the catalytic subunit of the deadenylase and that Pop2...

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Detalhes bibliográficos
Main Authors: Tucker, Morgan, Staples, Robin R., Valencia-Sanchez, Marco A., Muhlrad, Denise, Parker, Roy
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC125913/
https://ncbi.nlm.nih.gov/pubmed/11889048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.6.1427
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