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Central role of Drosophila SU(VAR)3–9 in histone H3-K9 methylation and heterochromatic gene silencing
Su(var)3–9 is a dominant modifier of heterochromatin-induced gene silencing. Like its mammalian and Schizosaccharomyces pombe homologues, Su(var) 3–9 encodes a histone methyltransferase (HMTase), which selectively methylates histone H3 at lysine 9 (H3-K9). In Su(var)3–9 null mutants, H3-K9 methylati...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2002
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125909/ https://ncbi.nlm.nih.gov/pubmed/11867540 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.5.1121 |
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