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The roX genes encode redundant male-specific lethal transcripts required for targeting of the MSL complex

The roX1 and roX2 genes of Drosophila produce male-specific non-coding RNAs that co-localize with the Male-Specific Lethal (MSL) protein complex. This complex mediates up-regulation of the male X chromo some by increasing histone H4 acetylation, thus contributing to the equalization of X-linked gene...

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Auteurs principaux: Meller, Victoria H., Rattner, Barbara P.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC125901/
https://ncbi.nlm.nih.gov/pubmed/11867536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.5.1084
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