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Hyperacetylation of chromatin at the ADH2 promoter allows Adr1 to bind in repressed conditions

We report that in vivo increased acetylation of the repressed Saccharomyces cerevisiae ADH2 promoter chromatin, as obtained by disrupting the genes for the two deacetylases HDA1 and RPD3, destabilizes the structure of the TATA box-containing nucleosome. This acetylation-dependent chromatin remodelin...

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Bibliografske podrobnosti
izdano v:EMBO J
Principais autores: Verdone, Loredana, Wu, Jiansheng, Riper, Kristen van, Kacherovsky, Nataly, Vogelauer, Maria, Young, Elton T., Grunstein, Michael, Mauro, Ernesto Di, Caserta, Micaela
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2002
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125900/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11867538/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/21.5.1101
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