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C/EBPα triggers proteasome-dependent degradation of cdk4 during growth arrest

CCAAT/enhancer binding protein alpha (C/EBPα) causes growth arrest via direct interaction with the cyclin-dependent kinases cdk2 and cdk4. In this paper, we present evidence showing that C/EBPα enhances a proteasome-dependent degradation of cdk4 during growth arrest in liver of newborn mice and in c...

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Detalles Bibliográficos
Publicado en:EMBO J
Principais autores: Wang, Hongmei, Goode, Triona, Iakova, Polina, Albrecht, Jeffrey H., Timchenko, Nikolai A.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2002
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125893/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11867521/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/21.5.930
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